产品货号：
Z37545
中文名称：
HFE2抗体
英文名称：
Anti-HFE2 Antibody (Clone#1D7)
产品规格：
100μg(vial)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HFE2 Antibody (Clone#1D7) |
| 指标别名 | Hemochromatosis type 2 protein;Hemojuvelin;HFE2;HFE2A;HJV;JH;RGM domain family member C;RGMC |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | IP,FCM |
| 基因名称 | HFE2 |
| 克隆号 | 1D7 |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant human RGMC (aa 36-398). |
| 计算分子量 | 45kDa |
| 成分 | Each vial contains 0.02% sodium azide. |
| 纯化方式 | Protein G-affinity purified. |
| 浓度 | 0.5～1mg/mL,actual concentration vary by lot.Use suggested dilution ratio to decide dilution procedure. |
| 产品形态 | 溶液 |
| 背景资料 | Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals.It is a member of the repulsive guidance molecule family of proteins.The product of this gene is involved in iron metabolism.It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression.It could also represent the cellular receptor for hepcidin.Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein.Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Defects in this gene are the cause of hemochromatosis type 2A,also called juvenile hemochromatosis (JH).JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism,hepatic fibrosis or cirrhosis and cardiomyopathy,occurring typically before age of 30. |
| Uniprot ID | Q6ZVN8 |
| 基因名全称 | Hemojuvelin |
| 蛋白名全称 | Hemojuvelin (HFE2) |
| 推荐稀释比 | User need to optimize the dilution ratio for this antibody |
相关搜索：HFE2抗体，HFE2单抗，Anti-HFE2 Antibody (Clone#1D7)