产品货号：
Z37451
中文名称：
Hu Nectin-2/PVRL2/NECTIN2 Purified抗体
英文名称：
Anti-Hu Nectin-2/PVRL2/NECTIN2 Purified Antibody (Clone#R2.525)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu Nectin-2/PVRL2/NECTIN2 Purified Antibody (Clone#R2.525) |
| 指标别名 | CD112;Herpes virus entry mediator B;Herpesvirus entry mediator B;HVEB;Nectin-2;PRR2;PVRL2;PVRR2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,IHC-F |
| 基因名称 | NECTIN2 |
| 克隆号 | R2.525 |
| 抗体来源 | Mouse |
| 免疫原 | NIH/3T3 cells transfected with human Nectin-2.The mouse monoclonal antibody R2.525 recognizes an extracellular epitope on CD112,a type I transmembrane glycoprotein expressed by myelomonocytic and megakaryocytic cells,and by CD34+ hematopoietic progenitors. |
| 计算分子量 | 58kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD112,also known as nectin-2,is a transmembrane glycoprotein involved in organization of adherens junctions.It also serves as a target molecule for entry of certain strains of herpes simplex virus (HSV) and pseudorabies virus (PRV).It is homologous to CD155,which serves as a target molecule for polio virus.CD112 seems to play a role in neural tube formation,with N-cadherin.Inside the cell,CD112 is connected with actin cytoskeleton through afadin.Variations in the CD112 gene have been associated with differences in the severity of multiple sclerosis.Alternate transcriptional splice variants,encoding different isoforms,have been characterized. |
| Uniprot ID | Q92692 |
| 基因名全称 | Nectin cell adhesion molecule 2 |
| 蛋白名全称 | Nectin-2 |
| 推荐稀释比 | Flow cytometry:1～4μg/mL. |
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