产品货号：
Z37447
中文名称：
Hu NKG2D/KLRK1 Purified Azide Free抗体
英文名称：
Anti-Hu NKG2D/KLRK1 Purified Azide Free Antibody (Clone#1D11)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu NKG2D/KLRK1 Purified Azide Free Antibody (Clone#1D11) |
| 指标别名 | killer cell lectin like receptor K1;CD314;D12S2489E;KLR;NKG2-D;NKG2D;KLRK1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,IHC-F,Functional Assay |
| 基因名称 | KLRK1 |
| 克隆号 | 1D11 |
| 抗体来源 | Mouse |
| 免疫原 | NKL cell line.The mouse monoclonal antibody 1D11 recognizes an extracellular epitope of CD314/NKG2D,a 42kDa C-type lectin-like activating receptor expressed by NK cells,gamma/delta T cells,and CD8+ T cells. |
| 计算分子量 | 25kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,azide-free |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD314,also known as NKG2D (natural killer receptor G2D) or KLRK1 (killer cell lectin-like receptor subfamily K,member 1),is a homodimeric C-type lectin-like activating receptor and costimulator with type II membrane orientation (C teminus extracellular).CD314 homodimers are associated with DAP10,a membrane adaptor protein that signals similar to CD28 by recruitment of phosphatidylinositol 3-kinase.Engagement of CD314 amplifies antigen-specific T cell responses in CD314-positive T cell populations.In NK cells,CD314 is a primary activating receptor.As CD314 ligands the MHC class-I chain-related proteins A and B (MICA,MICB) and UL16-binding proteins (ULBPs) have been identified. |
| Uniprot ID | P26718 |
| 基因名全称 | Killer cell lectin like receptor K1 |
| 蛋白名全称 | NKG2-D type II integral membrane protein |
| 推荐稀释比 | Functional application:Blocking of ligand binding. Immunohistochemistry:5～10μg/mL. Flow cytometry:1～4μg/mL |
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