产品货号：
Z37402
中文名称：
IFITM3抗体(N-term)
英文名称：
Anti-IFITM3 Antibody(N-term)(Clone#1082CT14.1.3.1)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IFITM3 Antibody (N-term) (Clone#1082CT14.1.3.1) |
| 指标别名 | 1 8U;Fragilis;IFITM3;IP15 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | IFITM3 |
| 克隆号 | 1082CT14.1.3.1 |
| 抗体来源 | Mouse |
| 免疫原 | This IFITM3 antibody is generated from a mouse immunized with a recombinant protein KLH conjugated synthetic peptide between 1-133 amino acids from the N-terminal region of human IFITM3. |
| 计算分子量 | 15kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis.Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes.May inactivate new enveloped viruses which buds out of the infected cell,by letting them go out with a cholesterol depleted membrane.Active against multiple viruses,including influenza A virus,SARS coronavirus (SARS-CoV),Marburg virus (MARV) and Ebola virus (EBOV),Dengue virus (DNV),West Nile virus (WNV),human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV).Can inhibit:influenza virus hemagglutinin protein-mediated viral entry,MARV and EBOV GP1,2- mediated viral entry,SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry.Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase).Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pHin phagocytic endosomes thus establishing an antiviral state. |
| Uniprot ID | Q01628 |
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