产品货号：
Z37150
中文名称：
FMR1抗体
英文名称：
Anti-FMR1 Antibody (Clone#OTI1C6)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FMR1 Antibody (Clone#OTI1C6) |
| 指标别名 | FMR1;FMRP;fragile X mental retardation 1;FRAXA;POF;POF1;Protein FMR 1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,monkey,mouse,rat,dog |
| 应用范围 | WB,IHC,IF,FCM |
| 基因名称 | FMR1 |
| 克隆号 | OTI1C6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 36-279 of human FMR1(NP_002015) produced in E.coli. |
| 实际分子量 | 71KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein°Called fragile X mentalretardation protein,or FMRP.This protein,most commonly found in the brain,is essential for normal°Cognitive development and female reproductive function.Mutations of this gene can lead to fragile X syndrome,mental retardation,premature ovarian failure,autism,Parkinson's disease,developmental delays and other cognitive deficits.The protein encoded by this gene binds RNA and is associated with polysomes.Additionally,the encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6～53 copies,but an expansion to 55-230 repeats is the cause of fragile X syndrome.Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1).Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
| Uniprot ID | Q06787 |
| 基因名全称 | fragile X mental retardation 1 |
| 蛋白名全称 | Synaptic functional regulator FMR1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:150 Immunofluorescence (IF) 1:100 Flow cytometry (FCM) 1:100 |
相关搜索：FMR1抗体，FMR1单抗，Anti-FMR1 Antibody (Clone#OTI1C6)