产品货号：
Z37149
中文名称：
FLT3抗体
英文名称：
Anti-FLT3 Antibody (Clone#OTI7D6)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FLT3 Antibody (Clone#OTI7D6) |
| 指标别名 | CD135;FL cytokine receptor;FLK2;FLT 3;FLT3;Fms like tyrosine kinase 3;fms related tyrosine kinase 3;Stem cell tyrosine kinase 1;STK 1;STK1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB |
| 基因名称 | FLT3 |
| 克隆号 | OTI7D6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 169-444 of human FLT3(NP_004110) produced in E.coli. |
| 实际分子量 | 112.7KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3),receptor-type tyrosine-protein kinase FLT3,or fetal liver kinase-2 (Flk2) is a protein that in humans is encoded by the FLT3 gene.This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis.This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain,which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor.The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,proliferation,and differentiation of hematopoietic cells in bone marrow.Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. |
| Uniprot ID | P36888 |
| 基因名全称 | fms related receptor tyrosine kinase 3 |
| 蛋白名全称 | Receptor-type tyrosine-protein kinase FLT3 |
| 推荐稀释比 | Western blot (WB) 1:500 |
相关搜索：FLT3抗体，FLT3单抗，Anti-FLT3 Antibody (Clone#OTI7D6)