产品货号:
Z37135
中文名称:
FMR1抗体
英文名称:
Anti-FMR1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FMR1 Antibody |
指标别名 | FMR1;FMRP;fragile X mental retardation 1;FRAXA;POF;POF1;Protein FMR 1 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF |
基因名称 | FMR1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human FMRP |
实际分子量 | 71~73KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | FMR1 (fragile X mental retardation 1) is a human gene that codes for a protein°Called fragile X mentalretardation protein,or FMRP.This protein,most commonly found in the brain,is essential for normal°Cognitive development and female reproductive function.Mutations of this gene can lead to fragile X syndrome,mental retardation,premature ovarian failure,autism,Parkinson's disease,developmental delays and other cognitive deficits.The protein encoded by this gene binds RNA and is associated with polysomes.Additionally,the encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm.A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6~53 copies,but an expansion to 55-230 repeats is the cause of fragile X syndrome.Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1).Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. |
Uniprot ID | Q06787 |
基因名全称 | Fragile X mental retardation protein 1 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
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