产品货号：
Z37051
中文名称：
RASGAP/RASA1抗体
英文名称：
Anti-RASGAP/RASA1 Antibody (Clone#OTI1H2)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RASGAP/RASA1 Antibody (Clone#OTI1H2) |
| 指标别名 | CM AVM;CMAVM;GAP;GTPase activating protein;p120GAP;p120RASGAP;PKWS;Ras p21 protein activator;RASA;RASA1;RASGAP |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IF |
| 基因名称 | RASA1 |
| 克隆号 | OTI1H2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Full length human recombinant rotein of human RASA1(NP_002881) produced in HEK293T cell. |
| 实际分子量 | 116.2KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins.The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart.Acting as a suppressor of RAS function,the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS,thereby allowing control of cellular proliferation and differentiation.Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas.Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome.Alternative splicing results in two isoforms where the shorter isoform,lacking the N-terminal hydrophobic region but retaining the same activity,appears to be abundantly expressed in placental but not adult tissues.[provided by RefSeq,May 2012] |
| Uniprot ID | P20936 |
| 基因名全称 | Ras GTPase-activating protein 1|GAP|GTPase-activating protein|RasGAP|Ras p21 protein activator|p120GAP |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunofluorescence (IF) 1:100 |
相关搜索：RASGAP/RASA1抗体，RASGAP抗体，RASA1单抗，Anti-RASGAP/RASA1 Antibody (Clone#OTI1H2)