产品货号：
Z37016
中文名称：
PCNA抗体
英文名称：
Anti-PCNA Antibody (Clone#1655CT506.10.26)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PCNA Antibody (Clone#1655CT506.10.26) |
| 指标别名 | PCNA |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM,IHC |
| 基因名称 | PCNA |
| 克隆号 | 1655CT506.10.26 |
| 抗体来源 | Mouse |
| 免疫原 | This PCNA antibody is generated from a mouse immunized with a recombinant protein of human PCNA. |
| 计算分子量 | 29kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.Induces a robust stimulatory effect on the 3'- 5' exonuclease and 3'-phosphodiesterase,but not apurinic- apyrimidinic (AP) endonuclease,APEX2 activities.Has to be loaded onto DNA in order to be able to stimulate APEX2.Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways.Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair:Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases,while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion. |
| Uniprot ID | P12004 |
相关搜索：PCNA抗体，PCNA单抗，Anti-PCNA Antibody (Clone#1655CT506.10.26)