产品货号：
Z37011
中文名称：
Hu KIR2DL5A Purified抗体
英文名称：
Anti-Hu KIR2DL5A Purified Antibody (Clone#UP-R1)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu KIR2DL5A Purified Antibody (Clone#UP-R1) |
| 指标别名 | KIR2DL5A;CD158F;CD158F1;KIR2DL5;KIR2DL5.1;KIR2DL5.3 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,ICC |
| 基因名称 | KIR2DL5A |
| 克隆号 | UP-R1 |
| 抗体来源 | Mouse |
| 免疫原 | Human CD158f-Ig fusion protein.The mouse monoclonal antibody UP-R1 recognizes an extracellular epitope on CD158f (KIR2DL5),a 60kDa glycoprotein serving as a HLA class I ligand,and mainly expressed on a subset of NK cells and a small population of T cells.Its expression is highly polymorphic between individuals. |
| 计算分子量 | 41kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD158f,also known as KIR2DL5,is a polymorphic 60kDa transmembrane glycoprotein with two Ig-like extracellular domains by which it recognize HLA class I molecules.Its long intracellular domain contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that upon extracellular ligand-mediated phosphorylation serve as docking sites for inhibitory phosphatases,which results in blocking natural cytotoxicity as well as antibody-dependent cytotoxicity of the particular NK cell,and its adhesion toward target cells.Together with other killer inhibitory receptors CD158f is important for immunological tolerance to discriminate between normal and abnormal cells.Besides NK cells it is expressed on a small population of cytotoxic T cells.Expression of CD158f alleles is highly variable in the population. |
| Uniprot ID | Q8N109 |
| 基因名全称 | Killer cell immunoglobulin like receptor,two Ig d |
| 蛋白名全称 | Killer cell immunoglobulin-like receptor 2DL5A |
| 推荐稀释比 | Flow cytometry:1～4μg/mL. |
相关搜索：Hu KIR2DL5A Purified抗体，Hu KIR2DL5A Purified单抗，Anti-Hu KIR2DL5A Purified Antibody (Clone#UP-R1)