产品货号：
Z36999
中文名称：
Hu CD63 Purified抗体
英文名称：
Anti-Hu CD63 Purified Antibody (Clone#MEM-259)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu CD63 Purified Antibody (Clone#MEM-259) |
| 指标别名 | CD63;CD63 antigen;CD63 molecule;Cell and organelle markers;Endosome Marker;Exosome marker;Granulophysin;LAMP 3;ME491;MLA1;OMA81H;Tetraspanin 30;Tspan 30;TSPAN30 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,IP,IHC,ICC |
| 基因名称 | CD63 |
| 克隆号 | MEM-259 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | HPB-ALL T cell line.The antibody MEM-259 reacts with an extracellular/luminal epitope of CD63 (LAMP-3),a 40～60kDa tetraspan glycoprotein expressed by granulocytes,platelets,T cells,monocytes/macrophages and endothelial cells.Cell surface exposition of CD63 is usually activation-dependent. |
| 计算分子量 | 26kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD63 (LAMP-3,lysosome-associated membrane protein-3),a glycoprotein of tetraspanin family,is present in late endosomes,lysosomes and secretory vesicles of various cell types.It is also present in the plasma membrane,usually following cell activation.Hence,it has become an widely used basophil activation marker.In mast cells,however,CD63 exposition does not need their activation.CD63 interacts with integrins and affects phagocytosis and cell migration,it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels.CD63 also serves as a T-cell costimulation molecule.Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. |
| Uniprot ID | P08962 |
| 基因名全称 | CD63 molecule |
| 蛋白名全称 | CD63 antigen |
| 推荐稀释比 | Flow cytometry:2μg/mL;positive material:activated platelets,neutrophils and basophils. Immunohistochemistry (paraffin sections):10μg/mL;positive tissue:spleen. |
相关搜索：Hu CD63 Purified抗体，Hu CD63 Purified单抗，Anti-Hu CD63 Purified Antibody (Clone#MEM-259)