产品货号：
Z36998
中文名称：
Hu CD79A Purified抗体
英文名称：
Anti-Hu CD79A Purified Antibody (Clone#HM47)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hu CD79A Purified Antibody (Clone#HM47) |
| 指标别名 | CD79A;Ig alpha;IGA;MB 1;MB 1 membrane glycoprotein;MB1;Surface IgM associated protein |
| 克隆性 | Monoclonal |
| 检验物种 | dog,chicken,rabbit,guinea pig,horse,cow,mouse,rat,pig,primate,human |
| 应用范围 | FCM,IP,WB,IHC |
| 基因名称 | CD79A |
| 克隆号 | HM47 |
| 抗体来源 | Mouse |
| 免疫原 | Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a.The mouse monoclonal antibody HM47 reacts with intracellular domain of CD79a (Ig alpha),a 40～45kDa subunit of B cell antigen-specific receptor (BCR) and its early developmental forms. |
| 计算分子量 | 25kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD79a (Ig alpha,MB1) forms disulfide-linked heterodimer with CD79b (Ig beta).They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs),and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR).CD79a and b are the first components of BCR that are expressed developmentally.They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin.Subsequently,in pre-B cells,CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins.At the plasma cell stage,CD79a is present as an intracellular component.CD79a/b complex interacts with Src-family tyrosine kinase Lyn,which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling. |
| Uniprot ID | P11912 |
| 基因名全称 | CD79a molecule |
| 蛋白名全称 | B-cell antigen receptor complex-associated protein alpha chain |
| 推荐稀释比 | Flow cytometry:1～4μg/mL,intracellular staining. Western blotting:1～2μg/mL. |
相关搜索：Hu CD79A Purified抗体，Hu CD79A Purified单抗，Anti-Hu CD79A Purified Antibody (Clone#HM47)