产品货号：
Z36920
中文名称：
IDO1抗体
英文名称：
Anti-IDO1 Antibody (Clone#2E2.6)
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IDO1 Antibody (Clone#2E2.6) |
| 指标别名 | CD107B;IDO;IDO 1;IDO1;INDO;indoleamine 2;3 dioxygenase 1;Indoleamine 2;3-dioxygenase 1;Indoleamine-pyrrole 2;3-dioxygenase |
| 克隆性 | Monoclonal |
| 检验物种 | mouse |
| 应用范围 | ELISA,FCM,IF,IHC,SDS-PAGE,WB |
| 基因名称 | IDO1 |
| 克隆号 | 2E2.6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | IDO1 antibody was produced in mouse by repeated immunizations with mouse recombinant IDO1 protein followed by hybridoma development. |
| 计算分子量 | 45kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | Anti-IDO1 antibody was purified from ascites fluid by Protein A chromatography followed by extensive dialysis against the buffer stated above.IDO1 antibody is specific for mouse IDO1 protein.Mouse IDO1 does not react with human tissues.Cross-reactivity with IDO1 from other sources has not been determined. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Anti-IDO-1 antibody recognizes indoleamine 2,3-dioxygenase1 (IDO1) is a 41～42kD intracellular enzyme that catabolizes tryptophan into kynurenine.IDO1 modulates levels of the amino acid tryptophan,which is vital for cell growth,but is also involved in the suppression of the immune response.IDO1 effects on immune suppression are due to decreased tryptophan availability and the generation of tryptophan metabolites,resulting in negative effects on T lymphocytes,including proliferation,function and survival.IDO1 may be involved in the suppression of the immune response to tumors,and blocking the IDO1 pathway may be a potential target for immuno and cancer therapy.IDO1 is expressed in a wide variety of tissues and can be upregulated by interferon gamma and other inflammatory cytokines. |
| Uniprot ID | P28776 |
| 基因名全称 | Indoleamine 2,3-dioxygenase 1 |
| 推荐稀释比 | ELISA:1:5000 - 1:50000 Flow Cytometry:0.5-1x10^6 cells IHC:User Optimized IF Microscopy:1:50～1:100 IP:10～100μL WB:1:500～1:1500 |
相关搜索：IDO1抗体，IDO1单抗，Anti-IDO1 Antibody (Clone#2E2.6)