加入收藏
百奥莱博公司客服电话百奥莱博QQ百奥莱博QQ百奥莱博QQ
百奥莱博公司微信服务号

产品目录

所在位置:所有产品 > 抗体抗原 > 一抗 > RBX1抗体
RBX1抗体图片
产品货号:
Z36813
中文名称:
RBX1抗体
英文名称:
Anti-RBX1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
本产品仅可用于科研实验,严禁用于其他非科研用途!
抗体名称Anti-RBX1 Antibody
指标别名Protein ZYP;RBX1;Regulator of cullins 1;ring box 1;RING box protein 1;RING finger protein 75;RNF75;ROC1
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC/IF,IP,FCM
基因名称RBX1
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human ROC1 E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins,including proteins involved in cell cycle progression,signal transduction,transcription and transcription-coupled nucleotide excision repair.
实际分子量12KD
成分500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
纯化方式Affinity-chromatography
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料RING-box protein 1,also known as ROC1,is a protein that in humans is encoded by the RBX1 gene.This gene is mapped to chromosome 22q13.2 based on an alignment of the RBX1 sequence with the genomic sequence.ROC1 is recruited by cullin-1 to form a quaternary SCF (HOS)-ROC1 holoenzyme (with SKP1 and the BTRCP homolog HOS).SCF (HOS)-ROC1 binds IKK-beta-phosphorylated I-kappa-B-alpha and catalyzes its ubiquitination in the presence of ubiquitin,E1,and CDC34.Conclusively,ROC1 plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization.
Uniprot IDP62877
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:20~100ICC/IF
Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100
Immunocoprecipitation 1:20
Flow cytometry (FCM) 1:20

相关搜索:RBX1抗体RBX1单抗Anti-RBX1 Antibody
首页 |  关于我们 |  联系我们 |  在线咨询 |  网站地图
北京百奥莱博科技有限公司 京ICP备14007103号-3