产品货号:
Z36753
中文名称:
IkB Beta/NFKBIB抗体
英文名称:
Anti-IkB Beta/NFKBIB Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-IkB Beta/NFKBIB Antibody |
指标别名 | I kappa B beta;IkappaBbeta;IkB B;IkB beta;IKBB;NF kappa B inhibitor beta;NF kappa BIB;NFKBIB;TR interacting protein 9;TRIP 9;TRIP9 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ICC/IF,IP |
基因名称 | NFKBIB |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human IKB beta |
实际分子量 | 48KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | NF-kappa-B inhibitor beta,also known as IKBB or TRIP9,is a protein that in humans is encoded by the NFKBIB gene.The protein encoded by this gene belongs to the NF-kappa-B inhibitor family,which inhibit NF-kappa-B by complexing with,and trapping it in the cytoplasm.This gene is mapped to 19q13.2.It has been found that in vivo,NFKBIB serves both to inhibit and to facilitate the inflammatory response.NFKBIB degradation releases NF-kappa-B dimers,which upregulate proinflammatory target genes such as TNF-alpha.Surprisingly,absence of NFKBIB results in a dramatic reduction of TNF-alpha in response to lipopolysaccharide,even though activation of NF-kappa-B is normal. |
Uniprot ID | Q15653 |
基因名全称 | NF-kappa-B inhibitor beta |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 Immunocoprecipitation 1:20 |
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