产品货号：
Z36674
中文名称：
RNF2抗体
英文名称：
Anti-RNF2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RNF2 Antibody |
| 指标别名 | BAP 1;BAP1;DING;HIP2 interacting protein 3;HIPI3;Protein DinG;RING finger protein 1B;ring finger protein 2;RING finger protein BAP 1;RING1B;RING2;RNF2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | RNF2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human RING2/RING1B/RNF2 E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A,thereby playing a central role in histone code and gene regulation.H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. |
| 实际分子量 | 38KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | E3 ubiquitin-protein ligase RING2 is an enzyme that in humans is encoded by the RNF2 gene.Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation.The protein encoded by this gene is one of the PcG proteins.It has been shown to interact with,and suppress the activity of,transcription factor CP2 (TFCP2/CP2).Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis,as well as in cell proliferation in early development.This protein was also found to interact with huntingtin interacting protein 2 (HIP2),an ubiquitin-conjugating enzyme,and possess ubiquitin ligase activity. |
| Uniprot ID | Q99496 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：RNF2抗体，RNF2单抗，Anti-RNF2 Antibody