产品货号：
Z36639
中文名称：
RAG2抗体
英文名称：
Anti-RAG2 Antibody (Clone#4D5)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RAG2 Antibody (Clone#4D5) |
| 指标别名 | RAG 2;RAG2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,ELISA |
| 基因名称 | RAG2 |
| 克隆号 | 4D5 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Purified recombinant fragment of human RAG-2 (350-527aa) expressed in E.Coli. |
| 计算分子量 | 59KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Recombination activating gene 2,also known as RAG-2,is a protein that in humans is encoded by the RAG2 gene.This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development.This protein forms a complex with the product of the adjacent recombination activating gene 1,and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences.The recombination activating gene 1 component is thought to contain most of the catalytic activity,while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA.A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components,specifically with histone H3 that is trimethylated at lysine 4.Mutations in this gene cause Omenn syndrome,a form of severe combined immunodeficiency associated with autoimmune-like symptoms. |
| Uniprot ID | P55895 |
| 基因名全称 | V(D)J recombination-activating protein 2 |
| 蛋白名全称 | V(D)J recombination-activating protein 2 |
| 推荐稀释比 | WB 1:500～1:2000 ELISA 1:10000 |
相关搜索：RAG2抗体，RAG2单抗，Anti-RAG2 Antibody (Clone#4D5)