产品货号：
Z36513
中文名称：
RAB11A抗体
英文名称：
Anti-RAB11A Antibody (Clone#1565CT164.36.80)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RAB11A Antibody (Clone#1565CT164.36.80) |
| 指标别名 | Rab 11;RAB11;RAB11A;RAB11A/B;Ras related protein Rab 11A;YL8 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | RAB11A |
| 克隆号 | 1565CT164.36.80 |
| 抗体来源 | Mouse |
| 免疫原 | This RAB11A antibody is generated from a mouse immunized with a purified recombinant protein of human RAB11A. |
| 计算分子量 | 24kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | The small GTPases Rab are key regulators of intracellular membrane trafficking,from the formation of transport vesicles to their fusion with membranes.Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation,movement,tethering and fusion.That Rab regulates endocytic recycling.Acts as a major regulator of membrane delivery during cytokinesis.Together with MYO5B and RAB8A participates in epithelial cell polarization.Together with RAB3IP,RAB8A,the exocyst complex,PARD3,PRKCI,ANXA2,CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS),apical surface formation and lumenogenesis.Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells.Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane.Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane.Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes.May also play a role in melanosome transport and release from melanocytes. |
| Uniprot ID | P62491 |
相关搜索：RAB11A抗体，RAB11A单抗，Anti-RAB11A Antibody (Clone#1565CT164.36.80)