产品货号：
Z36464
中文名称：
PRDX1抗体
英文名称：
Anti-PRDX1 Antibody (Clone#8E7)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PRDX1 Antibody (Clone#8E7) |
| 指标别名 | MSP23;NKEF A;NKEFA;PAG;PAGA;PAGB;peroxiredoxin 1;PRDX1;PRX1;PRXI;TDPX2;Thioredoxin peroxidase 2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IF |
| 基因名称 | PRDX1 |
| 克隆号 | 8E7 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Recombinant Protein |
| 计算分子量 | 22KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | PRDX1(Peroxiredoxin 1),also called PRX1,PAGA or NKEFA,is a thiol reductase that plays critical roles in oxidative and thermal stress defense mechanisms through its abilities to metabolize H2O2 and act as a molecular chaperone,respectively.This gene encodes a member of the peroxiredoxin family of antioxidant enzymes,which reduce hydrogen peroxide and alkyl hydroperoxides.The PRDX1 gene is mapped on 1p34.1.Prdx1 was expressed in differentiating motor neuron cells in developing embryonic chicken and mouse spinal cords.mmunoprecipitation analysis showed that GDE2 interacted directly with PRDX1 in embryonic chicken spinal cord extracts and in transfected HEK293T cells.This protein may have a proliferative effect and play a role in cancer development or progression.In differentiating spinal cord,Prdx1 was required to activate Gde2 by reducing an intramolecular cystine bridge between the Gde2 N- and C-terminal domains.An intramolecular disulfide bond between the GDE2 N- and C-terminal domains inhibits GDE2 function,and that reduction of this cystine by PRDX1 activates GDE2 for the induction of motor neuron differentiation. |
| Uniprot ID | Q06830 |
| 基因名全称 | Peroxiredoxin-1 |
| 蛋白名全称 | Peroxiredoxin-1 |
| 推荐稀释比 | WB 1:1000～3000 IF 1:100～200 |
相关搜索：PRDX1抗体，PRDX1单抗，Anti-PRDX1 Antibody (Clone#8E7)