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产品目录

所在位置:所有产品 > 抗体抗原 > 一抗 > IRS1抗体
IRS1抗体图片
产品货号:
Z36420
中文名称:
IRS1抗体
英文名称:
Anti-IRS1 Antibody (Clone#10I3)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-IRS1 Antibody (Clone#10I3)
指标别名HIRS 1;IRS 1;IRS1;IRS-1
克隆性Monoclonal
检验物种human
应用范围WB,IHC,ICC/IF,FCM
基因名称IRS1
克隆号10I3
抗体来源Mouse
抗体类型IgG2a
免疫原E.coli-derived human IRS1 recombinant protein (Position:S1041-Q1242).Human IRS1 shares 78% and 80% amino acid (aa) sequence identity with mouse and rat IRS1,respectively.
实际分子量165~180KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式protein G purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Insulin receptor substrate 1(IRS-1) is a signalling adapter protein that in humans is encoded by the IRS-1 gene.It is mapped to 2q36.3.This gene exhibited no intrinsic enzyme activity,and it can serve as a docking protein involved in binding and activating other signal transduction molecules after being phosphorylated on tyrosine by insulin receptor kinase.IRS1 plays a key role in transmitting signals from the insulin and insulin-like growth factor-1(IGF-1) receptors to intracellular pathways PI3K/Akt and Erk MAP kinase pathways.IRS1 also plays important biological function for both metabolic and mitogenic(growth promoting) pathways.In addition to those,IRS1 is a key regulator of PI3K within malignant cells.
Uniprot IDP35568
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC.
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:IRS1抗体IRS1单抗Anti-IRS1 Antibody (Clone#10I3)
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