产品货号：
Z36209
中文名称：
PD-1/CD279/PDCD1抗体
英文名称：
Anti-PD-1/CD279/PDCD1 Antibody (Clone#OTI4F10)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PD-1/CD279/PDCD1 Antibody (Clone#OTI4F10) |
| 指标别名 | CD279;hPD 1;hPD l;PD 1;PD1;PD-1;PD-1/CD279;PDCD1;programmed cell death 1;Protein PD 1;SLEB2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IF,FCM |
| 基因名称 | PDCD1 |
| 克隆号 | OTI4F10 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Full length human recombinant protein of human PDCD1 (NP_005009) produced in HEK293T cell. |
| 实际分子量 | 29.2KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | PDCD1 (Programmed cell death 1),also called PD1,encodes a cell surface receptor that is a member of the B7 superfamily involved in immunomodulation.This gene is mapped to 2q37.3.PDCD1 acts as an inhibitory molecule on T cells after interacting with its ligands PDL1 and PDL2.The PDCD1 gene contains 5 exons.This protein is expressed in pro-B-cells and is thought to play a role in their differentiation.Using flow cytometric analysis,it has been found that expression of PDCD1 was upregulated on CD16-positive and CD16-negative monocytes,but not on dendritic cells,in viremic HIV-positive patients,but not in highly active antiretroviral therapy (HAART)-treated HIV-positive patients.PDCD1 upregulation in monocytes was induced by microbial Toll-like receptor ligands and inflammatory cytokines. |
| Uniprot ID | Q02242 |
| 基因名全称 | programmed cell death 1 |
| 蛋白名全称 | Programmed cell death protein 1 |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 Immunofluorescence (IF) 1:900 Flow cytometry (FCM) 1:50 |
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