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产品目录

PD-1/CD279/PDCD1抗体图片
产品货号:
Z36198
中文名称:
PD-1/CD279/PDCD1抗体
英文名称:
Anti-PD-1/CD279/PDCD1 Antibody (Clone#4D6)
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-PD-1/CD279/PDCD1 Antibody (Clone#4D6)
指标别名CD279;hPD 1;hPD l;PD 1;PD1;PD-1;PD-1/CD279;PDCD1;programmed cell death 1;Protein PD 1;SLEB2
克隆性Monoclonal
检验物种human
应用范围ELISA,WB,IHC,ICC,IF
基因名称PDCD1
克隆号4D6
抗体来源Mouse
抗体类型IgG1
免疫原PD-1 antibody was raised against the extracellular domain of human PD-1.
计算分子量32kDa
成分PD-1 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol.
纯化方式PD-1 Antibody is supplied as protein A purified IgG1.
浓度1mg/mL
产品形态溶液
保存条件4℃可保存3个月,-20℃可保存1年。
背景资料Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC).T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC.PD-1 can bind two different but related ligands,PDL-1 and PDL-2.Upon binding to either of these ligands,signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens.Evidence for this is seen in PD-1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.PD-1 is thus one of a growing number of immune checkpoint proteins.
Uniprot IDQ15116
基因名全称Programmed cell death 1
蛋白名全称Programmed cell death 1
推荐稀释比PD-1 antibody can be used for detection of PD-1 by Western blot at 0.25 ~ 0.5μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested.

相关搜索:PD-1/CD279/PDCD1抗体PD-1抗体CD279抗体PDCD1单抗Anti-PD-1/CD279/PDCD1 Antibody (Clone#4D6)
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