PD-1/CD279/PDCD1抗体

产品货号：

Z36197

中文名称：

PD-1/CD279/PDCD1抗体

英文名称：

Anti-PD-1/CD279/PDCD1 Antibody (Clone#7A11B1)

产品规格：

0.1mg

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-PD-1/CD279/PDCD1 Antibody (Clone#7A11B1)
指标别名	CD279;hPD 1;hPD l;PD 1;PD1;PD-1;PD-1/CD279;PDCD1;programmed cell death 1;Protein PD 1;SLEB2
克隆性	Monoclonal
检验物种	human,mouse,rat
应用范围	ELISA,WB,IHC,IF
基因名称	PDCD1
克隆号	7A11B1
抗体来源	Mouse
抗体类型	IgG1
免疫原	A~150 amino acid recombinant protein from near the amino terminus of mouse PD-1.
计算分子量	32kDa
成分	PD-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式	PD-1 Monoclonal Antibody is Protein A purified.
浓度	1mg/mL
产品形态	溶液
保存条件	PD-1 monoclonal antibody can be stored at -20℃,stable for one year.
背景资料	Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC).T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC.PD-1 can bind two different but related ligands,PDL-1 and PDL-2.Upon binding to either of these ligands,signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens.Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.Despite its predicted molecular weight,PD-1 often migrates at higher molecular weight in SDS-PAGE.
Uniprot ID	Q02242
基因名全称	Programmed cell death 1
蛋白名全称	Programmed cell death 1
推荐稀释比	PD-1 antibody can be used for detection of PD-1 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples.All other applications and species not yet tested.

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