PKA C alpha/PRKACA Purified抗体

产品货号：

Z36119

中文名称：

PKA C alpha/PRKACA Purified抗体

英文名称：

Anti-PKA C alpha/PRKACA Purified Antibody (Clone#6D2.1)

产品规格：

0.1mg(C100)

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-PKA C alpha/PRKACA Purified Antibody (Clone#6D2.1)
指标别名	PKA C alpha;PKACA;PRKACA
克隆性	Monoclonal
检验物种	human
应用范围	WB
基因名称	PRKACA
克隆号	6D2.1
抗体来源	Mouse
抗体类型	IgG1
免疫原	Peptide corresponding to amino acids ESPAQNTAHLDQFERIK of human proteinkinase A c alpha (PKAc alpha).The mouse monoclonal antibody 6D2.1 strongly reacts with human proteinkinase A (an intracellular antigen) catalytic (PKAc) alpha subunit,and weakly with PKAc gamma subunit (both around 40kDa).The recognized epitope of PKAc alpha is identical between man,sheep,pig,ox and dog.
计算分子量	41kDa
成分	Phosphate buffered saline (PBS),pH7.4,15mM sodium azide
纯化方式	Purified by protein-A affinity chromatography.
浓度	1mg/mL
产品形态	溶液
保存条件	Store at 2～8℃.Do not freeze.
背景资料	Protein kinase A (PKA,cAMP-dependent protein kinase) is a key element of a ubiquitous signaling pathway important in the cell cycle,cellular communication,memory formation and behavior.PKA is composed of two catalytic (PKAc;proteinkinase A catalytic subunit) and two regulatory subunits (PKAr).Upon binding cAMP,the complex dissociates to PKAr dimer and two activated PKAc ser/thr protein kinase catalytic monomers.The released PKAc can translocate into the nucleus and exert a regulatory role in the activation of multiple nuclear hormone receptors.However,PKAc-mediated activation of tonicity-dependent gene expression is cAMP independent.Humans express three types of PKAc subunit每;PKAc alpha is present in most human tissues,PKAc beta and gamma are tissue-specific,the later is found in testes.
Uniprot ID	P17612
基因名全称	Protein kinase cAMP-activated catalytic subunit al
蛋白名全称	cAMP-dependent protein kinase catalytic subunit alpha
推荐稀释比	Western blotting:1μg/mL;positive control:HeLa human cervix carcinoma cell line.To detect PKAc gamma,use a more concentrated lysate from a tissue expressing this subunit (testis).

产品目录