产品货号:
Z36035
中文名称:
PAK1抗体
英文名称:
Anti-PAK1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PAK1 Antibody |
指标别名 | Alpha PAK;p21 activated kinase 1;p65 PAK;PAK 1;PAK1;PAKalpha |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | PAK1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human PAK1 The activated kinase acts on a variety of targets.Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway.Activated by CDC42 and RAC1.Involved in dissolution of stress fibers and reorganization of focal complexes.Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. |
实际分子量 | 68KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Serine/threonine-protein kinase PAK 1 is an enzyme that in humans is encoded by the PAK1 gene.PAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling.PAK proteins,a family of serine/threonine p21-activated kinases,include PAK1,PAK2,PAK3 and PAK4.These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities.PAK1 regulates cell motility and morphology.Alternative transcripts of this gene have been found,but their full-length natures have not yet been determined.The PAK1 gene is mapped to 11q13-q14 by inclusion within a mapped clone. |
Uniprot ID | Q13153 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
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