产品货号：
Z35893
中文名称：
PIAS1/PIAS2抗体
英文名称：
Anti-PIAS1/PIAS2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PIAS1/PIAS2 Antibody |
| 指标别名 | protein inhibitor of activated STAT 1;DDXBP1;GBP;GU/RH-II;ZMIZ3;PIAS1;PIAS2 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | PIAS1/PIAS2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human PIAS1+PIAS2+PIAS3 |
| 实际分子量 | 76KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene.It is mapped to 15q23.This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1(signal transducer and activator of transcription-1)] family.This member contains a putative zinc-binding motif and a highly acidic region.PIAS1 inhibited STAT1-mediated gene activation in response to interferon when expressed in mammalian cells.It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.On the other hand,PIAS1 also can function as a SUMO ligase,or possibly as a tightly bound regulator of it,toward p53. |
| Uniprot ID | O75925/O75928 |
| 基因名全称 | E3 SUMO-protein ligase PIAS1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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