产品货号:
Z35854
中文名称:
PD-L1/CD274抗体
英文名称:
Anti-PD-L1/CD274 Antibody (Clone#6H10)
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PD-L1/CD274 Antibody (Clone#6H10) |
指标别名 | B7 H;B7 H1;B7 homolog 1;B7H1;CD274;CD274 molecule;PD L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;PD-L1/CD274;Programmed death ligand 1 |
克隆性 | Monoclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,ICC,IF |
基因名称 | CD274 |
克隆号 | 6H10 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Anti-PD-L1 antibody was raised against the extracellular domain of human PD-L1. |
计算分子量 | 33kDa |
成分 | PD-L1 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol. |
纯化方式 | PD-L1 Antibody is supplied as protein A purified IgG1. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | PD-L1 plays a critical role in induction and maintenance of immune tolerance to self.As a ligand for the inhibitory receptor PDCD1/CD279,PD-L1 modulates the activation threshold of T-cells and limits T-cell effector response (1).The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (2,3).Through a yet unknown activating receptor,it may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (4). |
Uniprot ID | Q9NZQ7 |
基因名全称 | Programmed cell death 1 ligand |
蛋白名全称 | Programmed cell death 1 ligand |
推荐稀释比 | WB:0.25 ~ 4μg/mL;IF:2μg/mL;IHC:5μg/mL;ICC:1μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunohistochemistry,Immunocytochemistry and Immunofluorescence in human samples.All other applications and species not yet tested. |
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