产品货号:
Z35828
中文名称:
MYD88抗体
英文名称:
Anti-MYD88 Antibody (Clone#OTI1B4)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MYD88 Antibody (Clone#OTI1B4) |
指标别名 | MYD88;MYD88D |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IF,FCM |
基因名称 | MYD88 |
克隆号 | OTI1B4 |
抗体来源 | Mouse |
抗体类型 | IgG2a |
免疫原 | Full length human recombinant protein of human MYD88 (NP_002459) produced in HEK293T cell. |
实际分子量 | 33.1KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88),is a protein that,in humans,is encoded by the MYD88 gene.MyD88 is a key downstream adapter for most Toll-like receptors (TLRs) and interleukin-1 receptors (IL1Rs).And it is mapped on 3p22.2.MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response.This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways.Overexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter.The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP.Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death,and do so in a way that might not compromise tissue repair or host defense against pathogens. |
Uniprot ID | Q99836 |
基因名全称 | MYD88 innate immune signal transduction adaptor |
蛋白名全称 | Myeloid differentiation primary response protein MyD88 |
推荐稀释比 | Western blot (WB) 1:2000 Immunofluorescence (IF) 1:100 Flow cytometry (FCM) 1:100 |
相关搜索:MYD88抗体,MYD88单抗,Anti-MYD88 Antibody (Clone#OTI1B4)