产品货号：
Z35815
中文名称：
MYD88抗体
英文名称：
Anti-MYD88 Antibody (Clone#2E9C2)
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MYD88 Antibody (Clone#2E9C2) |
| 指标别名 | MYD88;MYD88D |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | MYD88 |
| 克隆号 | 2E9C2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Mouse monoclonal MyD88 antibody was raised against a recombinant protein corresponding to amino acids 176 to 280 of human MyD88. |
| 计算分子量 | 33kDa |
| 成分 | MyD88 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MyD88 Monoclonal Antibody is Protein A purified. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | MyD88 monoclonal antibody can be stored at -20℃,stable for one year. |
| 背景资料 | The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP.MyD88 has been identified as an adapter molecule in the IL-1 signaling pathway.MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-百B activation.MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor,which are members in the Toll/IL-1R family of receptors.Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18,and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors.MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin.MyD88 gene is expressed in many tissues. |
| Uniprot ID | Q99836 |
| 基因名全称 | Myeloid differentiation primary response gene (88) |
| 蛋白名全称 | Myeloid differentiation primary response gene (88) |
| 推荐稀释比 | MyD88 antibody can be used for detection of MyD88 by Western blot at 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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