
产品货号:
Z35813
中文名称:
MYBBP1A抗体
英文名称:
Anti-MYBBP1A Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MYBBP1A Antibody |
指标别名 | MYB binding protein (P160) 1a;Myb binding protein 1A;MYBBP1A;P160;PAP2 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | MYBBP1A |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human MYBBP1A May activate or repress transcription via interactions with sequence specific DNA-binding proteins.Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). |
实际分子量 | 149KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | The protooncogene MYB is predominantly expressed in immature hemopoietic cells where it has an essential role in hemopoietic cell proliferation and differentiation.Oncogenically activated forms of MYB is generally N- and/or C-terminal truncations of the normal MYB protein.Removal of the C terminus of MYB disrupts or deletes a region termed the negative regulatory domain (NRD),resulting in an increase in DNA binding,transactivation,and transformation by MYB.One feature of the NRD is a leucine zipper-like motif [PMID:8302594].Murine Myb-binding protein-1a (MYBBP1A),originally called P160,was identified by its ability to interact specifically with Myb via this leucine zipper-like motif.MYBBP1A modulates MYB activity upon binding to the MYB NRD [PMID:10644447,9447996]. |
Uniprot ID | Q9BQG0 |
推荐稀释比 | Western blot (WB) 1:400~800 |
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