产品货号:
Z35722
中文名称:
PERK/EIF2AK3抗体
英文名称:
Anti-PERK/EIF2AK3 Antibody (Clone#5G5)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PERK/EIF2AK3 Antibody (Clone#5G5) |
指标别名 | EIF2AK3;HRI;HsPEK;Pancreatic eIF2 alpha kinase;PEK;PERK;PERK/EIF2AK3;WRS |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | EIF2AK3 |
克隆号 | 5G5 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant fragment of human PERK expressed in E.Coli. |
计算分子量 | 125KD |
成分 | Ascitic fluid containing 0.03% sodium azide. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Eukaryotic translation initiation factor 2-alpha kinase 3,also known as protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK),is an enzyme that in humans is encoded by the EIF2AK3 gene.The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2,leading to its inactivation,and thus to a rapid reduction of translational initiation and repression of global protein synthesis.This protein is thought to modulate mitochondrial function.It is a type I membrane protein located in the endoplasmic reticulum (ER),where it is induced by ER stress caused by malfolded proteins.Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Uniprot ID | Q9NZJ5 |
基因名全称 | Eukaryotic translation initiation factor 2-alpha kinase 3 |
蛋白名全称 | Eukaryotic translation initiation factor 2-alpha kinase 3 |
推荐稀释比 | WB 1:500~1:2000 ELISA 1:10000 |
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