产品货号:
Z35618
中文名称:
MUC5B抗体
英文名称:
Anti-MUC5B Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MUC5B Antibody |
指标别名 | MG1;MUC5;MUC5B;MUC9 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | MUC5B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human MUC5B |
实际分子量 | 596KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Mucins are a group of high molecular weight glycoproteins consisting of a mucin core protein and O-linked carbohydrates.The Mucin 5B gene,which contains a 3' cis-element,is one of the four mucin genes mapped to human chromosome 11p15.5.Although Mucin 5B is the prominent human gallbladder mucin,it is also expressed and secreted in the colon.In addition,Mucin 5B is expressed in non-inflammed middle ears and normal esophagus,and is upregulated by chronic inflammation and highly secreted in the diseased middle ear.Mucin 5B is abnormally expressed in gastric carcinomatous tissues.Its expression in gastric cancer cells is controlled by a highly active distal promoter,which is upregulated by protein kinase C and repressed under the influence of methylation.Mucous differentiation and expression of Mucin 5B is retinoic acid- (RA) or retinol-dependent.RA control of mucin gene is mediated by the retinoid acid receptor RARa and,to a lesser extent,by RARg.The correlation of mucin protein levels in human cervical mucous with the peak at midcycle suggests that mucin may be important in sperm transit to the uterus. |
Uniprot ID | Q9HC84 |
推荐稀释比 | Western blot (WB) 1:500~2000 |
相关搜索:MUC5B抗体,MUC5B单抗,Anti-MUC5B Antibody