产品货号:
Z35570
中文名称:
PLK1抗体
英文名称:
Anti-PLK1 Antibody (Clone#OTI3F12)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PLK1 Antibody (Clone#OTI3F12) |
指标别名 | PLK;PLK 1;PLK1;Polo like kinase 1;STPK13 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,FCM |
基因名称 | PLK1 |
克隆号 | OTI3F12 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full-length protein expressed in 293T cell transfected with human PLK1 expression vector |
实际分子量 | 68.1KD |
成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | Serine/threonine-protein kinase PLK1,also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13(STPK13),is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene.Plk1 is an early trigger for G2/M transition.It supports the functional maturation of the centrosome in late G2/early prophaseand establishment of the bipolar spindle.Also,Plk1 phosphorylates and activates cdc25C,a phosphatase that dephosphorylates and activates the cyclinB/cdc2 complex.Studies have shown that the loss of PLK1 expression can inducepro-apoptotic pathways and inhibit growth.Based on yeast and murine studies of meiosis,human PLK1 may also have a regulatory function in meiosis. |
Uniprot ID | P53350 |
基因名全称 | polo-like kinase 1 |
蛋白名全称 | Serine/threonine-protein kinase PLK1 |
推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 Flow cytometry (FCM) 1:100 |
相关搜索:PLK1抗体,PLK1单抗,Anti-PLK1 Antibody (Clone#OTI3F12)