产品货号：
Z35472
中文名称：
nNOS/NOS1抗体
英文名称：
Anti-nNOS/NOS1 Antibody (Clone#NOS-B1)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-nNOS/NOS1 Antibody (Clone#NOS-B1) |
| 指标别名 | bNOS;Constitutive NOS;IHPS1;N NOS;NC NOS;Neuronal NOS;Nitric oxide synthase;brain;nNOS;NOS;NOS type I;NOS1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,goat,pig,rat |
| 应用范围 | WB |
| 基因名称 | NOS1 |
| 克隆号 | NOS-B1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Recombinant neuronal NOS fragment(amino acids 1-181) from rat brain. |
| 实际分子量 | 161KD |
| 成分 | 200μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Ascites |
| 浓度 | 200μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Nitric Oxide Synthase 1(NOS1,neuronal NOS,nNOS1) is a messenger molecule,mediating the effect of endothelium-derived relaxing factor in blood vessels and the cytotoxic actions of macrophages,and playing a part in neuronal communication in the brain.It may be involved in neuronal cell death and damage in neurological illness.nNOS1 localized to the 12q24.2 region of human chromosome 12.It splice variant,expressed in testis,that encodes an NH2-terminal truncated protein of 1098 amino acids.nNOS cDNA clones were shown to contain different 5' terminal exons spliced to a common exon 2.Genomic cloning and sequence analysis demonstrate that the unique exons are positioned within 300bp of each other but separated from exon 2 by an intron that is at least 20kb in length.The neuronal isoform of nitric oxide synthase is highly expressed in mammalian skeletal muscle,it suggested a specific role for NOS1 in the local metabolic inhibition of alpha-adrenergic vasoconstriction in active skeletal muscle.The novel gaseous neuromediator nitric oxide is though to play an important role in development and plasticity.Despite this,gene-knockout mice lacking neuronal(Type I) nitric oxide synthase exhibit relatively normal brain development and behavior. |
| Uniprot ID | P29475 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | nitric oxide synthase 1(neuronal) |
| 蛋白名全称 | Nitric oxide synthase,brain |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：nNOS/NOS1抗体，nNOS抗体，NOS1单抗，Anti-nNOS/NOS1 Antibody (Clone#NOS-B1)