产品货号：
Z35457
中文名称：
P-Selectin/SELP抗体
英文名称：
Anti-P-Selectin/SELP Antibody (Clone#AK4)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-P-Selectin/SELP Antibody (Clone#AK4) |
| 指标别名 | CD62;CD62P;GMP 140;GMP140;GMRP;Granule membrane protein 140;GRMP;LECAM3;P selectin;PADGEM;PSEL;P-selectin;SELP |
| 克隆性 | Monoclonal |
| 检验物种 | human,primate |
| 应用范围 | FCM,IP,WB,ICC |
| 基因名称 | SELP |
| 克隆号 | AK4 |
| 抗体来源 | Mouse |
| 免疫原 | Human platelets.The antibody AK4 recognizes an extracellular epitope of CD62P (P-selectin),a 140kD single chain type I transmembrane glycoprotein present in secretory alpha-granules in platelets,in Weibel-Palade bodies in endothelial cells and in megakaryocytes;it is relocated to the plasma membrane upon activation. |
| 计算分子量 | 91kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation.Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation.Both CD62P and PSGL-1 are extended glycoproteins that form homodimers.CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling,probably by increasing rebinding within a bond cluster. |
| Uniprot ID | P16109 |
| 基因名全称 | Selectin P |
| 蛋白名全称 | P-selectin |
| 推荐稀释比 | Flow cytometry:1.5μg/mL. |
相关搜索：P-Selectin/SELP抗体，P-Selectin抗体，SELP单抗，Anti-P-Selectin/SELP Antibody (Clone#AK4)