产品货号:
Z35293
中文名称:
p73/TP73抗体
英文名称:
Anti-p73/TP73 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-p73/TP73 Antibody |
指标别名 | tumor protein p73;P73;TP73 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF |
基因名称 | TP73 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human p73 |
实际分子量 | 73KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | p73,also known as tumor protein 73(TP73),encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development.It is mapped to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors,and thought to contain multiple tumor suppressor genes.The demonstration that this gene is monoallelically expressed (likely from the maternal allele),supports the notion that it is a candidate gene for neuroblastoma.Furthermore,recent finding are suggesting that over-expression of transcription factors involved in cell cycle regulation and synthesis of DNA in mammalian cells (e.g.:E2F-1) induces the expression of p73.In addition,p73 is a substrate of the c-Abl kinase and that the ability of c-Abl to phosphorylate p73 is markedly increased by gamma-irradiation. |
Uniprot ID | O15350 |
基因名全称 | Tumor protein p73 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 |
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