产品货号:
Z35284
中文名称:
P62/SQSTM1抗体
英文名称:
Anti-P62/SQSTM1 Antibody (Clone#21S51)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-P62/SQSTM1 Antibody (Clone#21S51) |
指标别名 | P62;P62/SQSTM1;sequestosome 1;SQSTM1;Ubiquitin binding protein p62 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ICC/IF,IP,FCM |
基因名称 | SQSTM1 |
克隆号 | 21S51 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human SQSTM1/p62 |
实际分子量 | 62KD |
成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | SQSTM1(Sequestosome-1),also known as Ubiquitin-Binding Protein P62 or P62,is a protein that in humans is encoded by the SQSTM1 gene.The Src homology type 2(SH2) domain is a highly conserved motif of about 100 amino acids which mediates protein-protein interactions by binding to phosphotyrosine.p56-lck,a T-cell-specific src family tyrosine kinase with an SH2 domain,is involved in T-cell signal transduction.The International Radiation Hybrid Mapping Consortium mapped the p62 gene to chromosome 5q35.Park et al.(1995) found that the p56-lck SH2 domain binds to p62 at the ser59 of p62 only when that serine is phosphorylated.Joung et al.(1996) expressed epitope-tagged p62 in Hela cells and showed that the expressed protein bound to the lck SH2 domain and that this binding was dependent on the N-terminal 50 amino acids of p62 but not on the tyrosine residue in this region. |
Uniprot ID | Q13501 |
基因名全称 | sequestosome 1 |
蛋白名全称 | Sequestosome-1 |
推荐稀释比 | Western blot (WB) 1:500~2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FCM 1:50 |
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