产品货号：
Z35139
中文名称：
NF2抗体
英文名称：
Anti-NF2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NF2 Antibody |
| 指标别名 | ACN;BANF;Merlin;Neurofibromin 2;neurofibromin 2 (merlin);NF2;SCH;Schwannomerlin;Schwannomin |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IP |
| 基因名称 | NF2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human NF2/Merlin Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway,a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. |
| 实际分子量 | 70KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Human merlin is coded by the gene NF2 in Chromosome 22.It is mapped to 22q12.2.This gene encodes a protein that is similar to some members of the ERM (ezrin,radixin,moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane.This gene product has been shown to interact with cell-surface proteins,proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport.This gene is expressed at high levels during embryonic development;in adults,significant expression is found in Schwann cells,meningeal cells,lens and nerve.Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities.Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. |
| Uniprot ID | P35240 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocoprecipitation 1:20 |
相关搜索：NF2抗体，NF2单抗，Anti-NF2 Antibody