产品货号:
Z35047
中文名称:
MGMT抗体
英文名称:
Anti-MGMT Antibody (Clone#OTI1B12)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MGMT Antibody (Clone#OTI1B12) |
指标别名 | MGMT |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | MGMT |
克隆号 | OTI1B12 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human MGMT (NP_002403) produced in E.coli. |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | Methylated-DNA-protein-cysteine methytransferase(MGMT) is an enzyme that in humans is encoded by the MGMT gene.O(6)-alkylguanine is the major mutagenic and carcinogenic lesion in DNA induced by simple alkylating mutagens.MGMT gene is mapped to chromosome 10.Rydberg et al.(1990) concluded that the methyltransferase gene spans at least 15kb.Gardner et al.(1991) refined the localization of the gene to 10q24.33-qter.Methylation of the gene's promoter plays a significant role in carcinogenesis. |
Uniprot ID | P16455 |
基因名全称 | O-6-methylguanine-DNA methyltransferase |
蛋白名全称 | Methylated-DNA--protein-cysteine methyltransferase |
推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索:MGMT抗体,MGMT单抗,Anti-MGMT Antibody (Clone#OTI1B12)