产品货号：
Z34859
中文名称：
Ms CD3 Purified抗体
英文名称：
Anti-Ms CD3 Purified Antibody (Clone#145-2C11)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Ms CD3 Purified Antibody (Clone#145-2C11) |
| 指标别名 | CD3;CD3 epsilon;CD3E;CD3-epsilon;T3E;TCRE |
| 克隆性 | Monoclonal |
| 检验物种 | mouse |
| 应用范围 | FCM,IP,IHC-F,ICC |
| 基因名称 | CD3E |
| 克隆号 | 145-2C11 |
| 抗体来源 | Hamster |
| 抗体类型 | IgG,κ |
| 免疫原 | Mouse BM10-37 cytotoxic T lymphocytes.The Armenian hamster monoclonal antibody 145-2C11 reacts with an extracellular epitope of murine CD3 (epsilon subunit).This antibody is commonly used as a phenotypic marker for murine T cells. |
| 计算分子量 | 21kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex.T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma,CD3 delta,CD3 epsilon and CD3 zeta.These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11.The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules.This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits.CD3 may play a role in TCR-induced growth arrest,cell survival and proliferation.The CD3 antigen is present on 68～82% of normal peripheral blood lymphocytes,65～85% of thymocytes and Purkynje cells in the cerebellum.It is never expressed on B or NK cells.Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. |
| Uniprot ID | P22646 |
| 基因名全称 | CD3 antigen,epsilon polypeptide |
| 蛋白名全称 | T-cell surface glycoprotein CD3 epsilon chain |
| 推荐稀释比 | Flow cytometry:1～2μg/mL (million cells). Immunoprecipitation:1～2μg/100～500μg protein in 1mL of a cell lysate. |
相关搜索：Ms CD3 Purified抗体，Ms CD3 Purified单抗，Anti-Ms CD3 Purified Antibody (Clone#145-2C11)