产品货号:
Z34854
中文名称:
Ms B7-2/CD86 Purified抗体
英文名称:
Anti-Ms B7-2/CD86 Purified Antibody (Clone#GL-1)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Ms B7-2/CD86 Purified Antibody (Clone#GL-1) |
指标别名 | Activation B7 2 antigen;B7 2;B70;BU63;CD28LG2;CD86;CD86 molecule;FUN 1;LAB72 |
克隆性 | Monoclonal |
检验物种 | mouse |
应用范围 | FCM,IP,IHC-F,ICC |
基因名称 | CD86 |
克隆号 | GL-1 |
抗体来源 | Rat |
免疫原 | LPS-activated CBA/Cs mouse splenic B cells.The rat monoclonal antibody GL-1 reacts with an extracellular epitope of CD86 (B7-2),a 70~80kDa type I transmembrane glycoprotein of immunoglobulin supergene family,expressed on professional antigen-presenting cells,such as dendritic cells,macrophages or activated B lymphocytes. |
计算分子量 | 35kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-G affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152).The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation,the both molecules can also substitute for each other in this process.The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet;there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response. |
Uniprot ID | P42082 |
基因名全称 | CD86 molecule |
蛋白名全称 | T-lymphocyte activation antigen CD86 |
推荐稀释比 | Flow cytometry:2μg/mL;positive control:murine splenocytes. |
相关搜索:Ms B7-2/CD86 Purified抗体,Ms B7-2抗体,CD86 Purified单抗,Anti-Ms B7-2/CD86 Purified Antibody (Clone#GL-1)