产品货号：
Z34816
中文名称：
STUB1抗体(C-term)
英文名称：
Anti-STUB1 Antibody(C-term)(Clone#1008CT12.4.1)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-STUB1 Antibody (C-term) (Clone#1008CT12.4.1) |
| 指标别名 | Antigen NY CO 7;CHIP;CLL associated antigen KW 8;HSPABP2;NY CO 7;SDCCAG7;STUB1;UBOX1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB |
| 基因名称 | STUB1 |
| 克隆号 | 1008CT12.4.1 |
| 抗体来源 | Mouse |
| 免疫原 | This STUB1 antibody is generated from a mouse immunized with a recombinant protein of human STUB1. |
| 计算分子量 | 35kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation.Collaborates with ATXN3 in the degradation of misfolded chaperone substrates:ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension.Ubiquitinates NOS1 in concert with Hsp70 and Hsp40.Modulates the activity of several chaperone complexes,including Hsp70,Hsc70 and Hsp90.Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.Mediates polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41','Lys-61' and 'Lys-81',thereby playing a role in base-excision repair:catalyzes polyubiquitination by amplifying the HUWE1/ARF- BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome.Mediates polyubiquitination of CYP3A4.Ubiquitinates EPHA2 and may regulate the receptor stability and activity through proteasomal degradation. |
| Uniprot ID | Q9UNE7 |
相关搜索：STUB1抗体(C-term)，STUB1单抗，Anti-STUB1 Antibody(C-term)(Clone#1008CT12.4.1)