产品货号：
Z34771
中文名称：
MEK3/MAP2K3 (Ab-189)抗体
英文名称：
Anti-MEK3/MAP2K3 (Ab-189) Antibody (Clone#OTI1H6)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MEK3/MAP2K3 (Ab-189) Antibody (Clone#OTI1H6) |
| 指标别名 | MAP kinase kinase 3;MAP2K3;MAPK/ERK kinase 3;MAPKK 3;MAPKK3;MEK 3;MEK3;MKK3;PRKMK3 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF |
| 基因名称 | MAP2K3 |
| 克隆号 | OTI1H6 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | Full length human recombinan protein of human MAP2K3(NP_659731) produced in HEK293T cell. |
| 实际分子量 | 39.1KD |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family.This kinase is activated by mitogenic and environmental stress,and participates in the MAP kinase-mediated signaling cascade.It phosphorylates and thus activates MAPK14/p38-MAPK.This kinase can be activated by insulin,and is necessary for the expression of glucose transporter.Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase,which thus leads to the constitutive activation of MAPK14,and confers oncogenic transformation of primary cells.The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis.Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.[provided by RefSeq,Jul 2008] |
| Uniprot ID | P46734 |
| 基因名全称 | mitogen-activated protein kinase kinase 3 |
| 蛋白名全称 | Dual specificity mitogen-activated protein kinase kinase 3(MAP kinase kinase 3/MAPKK 3) |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 Immunofluorescence (IF) 1:100 |
相关搜索：MEK3/MAP2K3 (Ab-189)抗体，MEK3抗体，MAP2K3 (Ab-189)单抗，Anti-MEK3/MAP2K3 (Ab-189) Antibody (Clone#OTI1H6)