产品货号:
Z34765
中文名称:
MEK3/6抗体
英文名称:
Anti-MEK3/6 Antibody (Clone#8A11-G11-G11)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MEK3/6 Antibody (Clone#8A11-G11-G11) |
指标别名 | MAP kinase kinase 6;MAP2K6;MAPK/ERK kinase 6;MAPKK 6;MAPKK6;MEK 6;MEK6;MKK6;PRKMK6;SAPKK3;MAP kinase kinase 3;MAPKK 3;MAPK/ERK kinase 3;MEK 3;SAPK kinase 2;SAPKK-2;SAPKK2;MAP2K3;MEK3;MKK3;PRKMK3;SKK2 |
克隆性 | Monoclonal |
检验物种 | human,rat |
应用范围 | WB,ELISA |
基因名称 | MAP2K3/MAP2K6 |
克隆号 | 8A11-G11-G11 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant human MKK6 protein fragments expressed in E.coli. |
计算分子量 | 37KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene.The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family.This kinase is activated by mitogenic and environmental stress,and participates in the MAP kinase-mediated signaling cascade.It phosphorylates and thus activates MAPK14/p38-MAPK.And this kinase can be activated by insulin,and is necessary for the expression of glucose transporter.Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase,which thus leads to the constitutive activation of MAPK14,and confers oncogenic transformation of primary cells.Rampoldi et al.(1997) localized the MAP2K3 gene to 17q11.2. |
Uniprot ID | P46734/P52564 |
基因名全称 | Dual specificity mitogen-activated protein kinase kinase 6 |
蛋白名全称 | Dual specificity mitogen-activated protein kinase kinase 6 |
推荐稀释比 | WB 1:500~2000 ELISA 1:10000~20000 |
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