产品货号：
Z34690
中文名称：
LARGE/LARGE1 Purified抗体
英文名称：
Anti-LARGE/LARGE1 Purified Antibody (Clone#LARGE-02)
产品规格：
0.1mg(C100)
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LARGE/LARGE1 Purified Antibody (Clone#LARGE-02) |
| 指标别名 | KIAA0609,LARGE,LARGE1,like glycosyltransferase,MDC1D |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | FCM,WB |
| 基因名称 | LARGE1 |
| 克隆号 | LARGE-02 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | Recombinant fragment of human LARGE1 (amino acids 35-142).The mouse monoclonal antibody LARGE-02 recognizes human LARGE1,a glycosyltransferase expressed mainly in the Golgi apparatus. |
| 计算分子量 | 88kDa |
| 成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
| 纯化方式 | Purified by protein-A affinity chromatography. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Store at 2～8℃.Do not freeze. |
| 背景资料 | LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan.Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation.Altered alpha-dystroglycan glycosylation may also play a role in cancer,as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells. |
| Uniprot ID | O95461 |
| 基因名全称 | LARGE xylosyl- and glucuronyltransferase 1 |
| 蛋白名全称 | LARGE xylosyl- and glucuronyltransferase 1 |
| 推荐稀释比 | Flow cytometry:1～5μg/mL.Intracellular staining. |
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