产品货号：
Z34617
中文名称：
MSH2抗体
英文名称：
Anti-MSH2 Antibody (Clone#6B4F7)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MSH2 Antibody (Clone#6B4F7) |
| 指标别名 | COCA1;FCC1;hMSH2;HNPCC;HNPCC1;LCFS2;MSH2;MutS protein homolog 2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | MSH2 |
| 克隆号 | 6B4F7 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human MSH2 recombinant protein (Position:Q337-N583).Human MSH2 shares 94% and 93% amino acid (aa) sequence identity with mouse and rat MSH2,respectively. |
| 实际分子量 | 105KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DNA mismatch repair protein Msh2,also known as MutS protein homolog 2 or MSH2,is a protein that in humans is encoded by the MSH2 gene,which is located on chromosome 2.MSH2 is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein,MSH2 which forms aheterodimer with MSH6 to make the human MutSα mismatch repair complex.It also dimerizes with MSH3 to form the MutSβ DNA repair complex.MSH2 is involved in many different forms of DNA repair,including transcription-coupled repair,homologous recombination,and base excision repair.It has been found that MSH2 may also be a coactivator of ESR1-dependent gene expression. |
| Uniprot ID | P43246 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | mutS homolog 2 |
| 蛋白名全称 | DNA mismatch repair protein Msh2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：MSH2抗体，MSH2单抗，Anti-MSH2 Antibody (Clone#6B4F7)