产品货号：
Z34614
中文名称：
MSH2抗体
英文名称：
Anti-MSH2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MSH2 Antibody |
| 指标别名 | COCA1;FCC1;hMSH2;HNPCC;HNPCC1;LCFS2;MSH2;MutS protein homolog 2 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM |
| 基因名称 | MSH2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human MSH2 MSH2 (MutS homologue 2) forms the hMutS- Alpha dimer with MSH6 and is an essential component of the mismatch repair process.hMutS- Alpha is part of the BRCA1-associated surveillance complex (BASC),a complex that also contains BRCA1,MLH1,ATM,BLM,PMS2 proteins and the Rad50-Mre11-NBS1 complex. |
| 实际分子量 | 105KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DNA mismatch repair protein Msh2,also known as MutS protein homolog 2 or MSH2,is a protein that in humans is encoded by the MSH2 gene,which is located on chromosome 2.MSH2 is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein,MSH2 which forms aheterodimer with MSH6 to make the human MutSα mismatch repair complex.It also dimerizes with MSH3 to form the MutSβ DNA repair complex.MSH2 is involved in many different forms of DNA repair,including transcription-coupled repair,homologous recombination,and base excision repair.It has been found that MSH2 may also be a coactivator of ESR1-dependent gene expression. |
| Uniprot ID | P43246 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Flow cytometry (FCM) 1:20 |
相关搜索：MSH2抗体，MSH2单抗，Anti-MSH2 Antibody