产品货号：
Z34574
中文名称：
MBD2抗体
英文名称：
Anti-MBD2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MBD2 Antibody |
| 指标别名 | Demethylase;DMTase;MBD2;NY CO 41 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | MBD2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human MBD2 Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides.Binds hemimethylated DNA as well.Recruits histone deacetylases and DNA methyltransferases. |
| 实际分子量 | 29KD/43KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene.It is mapped to 18q21.2.Human proteins MECP2,MBD1,MBD2,MBD3,and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD).Each of these proteins,with the exception of MBD3,is capable of binding specifically to methylated DNA.DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development.The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal.It is also reported that this protein functions as a demethylase to activate transcription,as DNA methylation causes gene silencing. |
| Uniprot ID | Q9UBB5 |
| 推荐稀释比 | Western blot (WB) 1:400～800 |
相关搜索：MBD2抗体，MBD2单抗，Anti-MBD2 Antibody