产品货号:
Z34548
中文名称:
Lamin A抗体
英文名称:
Anti-Lamin A Antibody (Clone#OTI3F6)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Lamin A Antibody (Clone#OTI3F6) |
指标别名 | 70kDa lamin;CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;HGPS;IDC;lamin A;lamin A/C;LDP1;LFP;LGMD1B;LMN1;LMNA;LMNC;Prelamin A/C;PRO1;progerin |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | LMNA |
克隆号 | OTI3F6 |
抗体来源 | Mouse |
抗体类型 | IgG2b |
免疫原 | Full length human recombinant protein of human LMNA (NP_733821) produced in HEK293T cell. |
实际分子量 | 74KD |
成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane.The lamin family of proteins make up the matrix and are highly conserved in evolution.During mitosis,the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated.Lamin proteins are thought to be involved in nuclear stability,chromatin structure and gene expression.Vertebrate lamins consist of two types,A and B.Alternative splicing results in multiple transcript variants.Mutations in this gene lead to several diseases:Emery-Dreifuss muscular dystrophy,familial partial lipodystrophy,limb girdle muscular dystrophy,dilated cardiomyopathy,Charcot-Marie-Tooth disease,and Hutchinson-Gilford progeria syndrome.[provided by RefSeq,Apr 2012] |
Uniprot ID | P02545 |
基因名全称 | Prelamin-A/C [Cleaved into:Lamin-A/C|70kDa lamin|Renal carcinoma antigen NY-REN-32] |
推荐稀释比 | Western blot (WB) 1:2000 |
相关搜索:Lamin A抗体,Lamin A单抗,Anti-Lamin A Antibody (Clone#OTI3F6)