产品货号：
Z34399
中文名称：
MFN1抗体
英文名称：
Anti-MFN1 Antibody (Clone#3H3)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MFN1 Antibody (Clone#3H3) |
| 指标别名 | Fzo homolog;hfzo1;hfzo2;MFN1;mitofusin 1;Transmembrane GTPase MFN1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,ICC/IF |
| 基因名称 | MFN1 |
| 克隆号 | 3H3 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminal of human Mitofusin 1 (23-49aa DQLLEFVTEGSHFVEATYKNPELDRIA),different from the related mouse and rat sequences by one amino acid. |
| 实际分子量 | 84KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | protein G purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene.It is an 80 90kDa mitochondrial member of the dynamin family of molecules.It is ubiquitously expressed,and found in the outer mitochondrial membrane.The protein encoded by this gene is a mediator of mitochondrial fusion,and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology.MFN1 is known to form oligomers,either with itself or MFN 2,and to undergo ubiquitination by MARCH5.MFN 1 has two key domains.One is a coiled°Coil region that mediates MFN 1:MFN 1/2 binding,and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion.Overexpression of MFN1 caused perinuclear mitochondrial clustering. |
| Uniprot ID | Q8IWA4 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | mitofusin 1 |
| 蛋白名全称 | Mitofusin-1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry in fixed cells 1:50～400 |
相关搜索：MFN1抗体，MFN1单抗，Anti-MFN1 Antibody (Clone#3H3)